Activation of Type I and III interferon signalling pathways occurs in lung epithelial cells infected with low pathogenic Avian influenza viruses

• Main Authors: Sugrue, Richard J., Yeo, Dawn S., Sutejo, Richard, Myaing, Myint Zu, Hui, Chen, Xia, Jiajia, Ko, Debbie, Tan, Boon Huan, Cheung, Peter Ching For
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Bacteria
• Online Access: https://hdl.handle.net/10356/95652; http://hdl.handle.net/10220/9368
• Institution: Nanyang Technological University

The host response to the low pathogenic avian influenza (LPAI) H5N2, H5N3 and H9N2 viruses were examined in A549, MDCK, and CEF cells using a systems-based approach. The H5N2 and H5N3 viruses replicated efficiently in A549 and MDCK cells, while the H9N2 virus replicated least efficiently in these ce...