Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors

• Main Authors: Andrews, Katherine T., Gupta, Archna P., Tran, Thanh N., Fairlie, David P., Gobert, Geoffrey N., Bozdech, Zbynek
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Microbiology
• Online Access: https://hdl.handle.net/10356/95689; http://hdl.handle.net/10220/9369
• Institution: Nanyang Technological University

Histone deacetylase (HDAC) inhibitors are being intensively pursued as potential new drugs for a range of diseases, including malaria. HDAC inhibitors are also important tools for the study of epigenetic mechanisms, transcriptional control, and other important cellular processes. In this study the e...