Structure of the C-terminal domain of the multifunctional ICP27 protein from herpes simplex virus 1

• Main Authors: Nordlund, Par, Patel, Vidhi, Dahlroth, Sue-Li, Rajakannan, Venkatachalam, Ho, Hai Ting, Cornvik, Tobias
• Other Authors: Dermody, T. S.
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: https://hdl.handle.net/10356/95866; http://hdl.handle.net/10220/38454
• Institution: Nanyang Technological University

Herpesviruses are nuclear-replicating viruses that have successfully evolved to evade the immune system of humans, establishing lifelong infections. ICP27 from herpes simplex virus is a multifunctional regulatory protein that is functionally conserved in all known human herpesviruses. It has the p...