A switch in infected erythrocyte deformability at the maturation and blood circulation of Plasmodium falciparum transmission stages

• Main Authors: Bischoff, Emmanuel, Ndour, Papa Alioune, Silvestrini, Francesco, Khattab, Ayman, Tibúrcio, Marta, Niang, Makhtar, Deplaine, Guillaume, Perrot, Sylvie, Vernick, Kenneth D., Milon, Geneviève, David, Peter H., Hardeman, Max, Sauerwein, Robert W., Preiser, Peter Rainer, Mercereau-Puijalon, Odile, Buffet, Pierre, Alano, Pietro, Lavazec, Catherine
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/95925; http://hdl.handle.net/10220/10789
• Institution: Nanyang Technological University

Achievement of malaria elimination requires development of novel strategies interfering with parasite transmission, including targeting the parasite sexual stages (gametocytes). The formation of Plasmodium falciparum gametocytes in the human host takes several days during which immature gametocyte-i...