An amine-reactive tetraphenylethylene derivative for protein detection in SDS-PAGE

• Main Authors: Yu, Yong, Qin, Anjun, Feng, Chao, Lu, Ping, Ng, Ka Ming, Luo, Kathy Qian, Tang, Ben Zhong
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/95973; http://hdl.handle.net/10220/10751
• Institution: Nanyang Technological University

A new aggregation-induced emission (AIE) compound 1,2-bis[4-(isothiocyanatomethyl)phenyl]-1,2-diphenylethene (2) was synthesized for use in SDS-PAGE. The molecule is practically nonemissive in solution but becomes highly emissive after reacting with the amine groups of the proteins by either the pre...