Rigidifying acyl carrier protein domain in iterative type I PKS CalE8 does not affect its function

• Main Authors: Lim, Jackwee, Sun, Huihua, Fan, Jing-Song, Hameed, Iman Fahim, Lescar, Julien, Liang, Zhao-Xun, Yang, Daiwen
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2013
• 主題: DRNTU::Science::Biological sciences
• 在線閱讀: https://hdl.handle.net/10356/96023; http://hdl.handle.net/10220/10787
• 機構: Nanyang Technological University

Acyl carrier protein (ACP) domains shuttle acyl intermediates among the catalytic domains of multidomain type I fatty acid synthase and polyketide synthase (PKS) systems. It is believed that the unique function of ACPs is associated with their dynamic property, but it remains to be fully elucidated...