A robust approach to extract biomedical events from literature

Motivation: The abundance of biomedical literature has attracted significant interest in novel methods to automatically extract biomedical relations from the literature. Until recently, most research was focused on extracting binary relations such as protein–protein interactions and drug–disease rel...

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Main Authors: Bui, Quoc-Chinh, Sloot, Peter M. A.
Other Authors: School of Computer Engineering
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/96085
http://hdl.handle.net/10220/10109
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-960852020-05-28T07:18:49Z A robust approach to extract biomedical events from literature Bui, Quoc-Chinh Sloot, Peter M. A. School of Computer Engineering Motivation: The abundance of biomedical literature has attracted significant interest in novel methods to automatically extract biomedical relations from the literature. Until recently, most research was focused on extracting binary relations such as protein–protein interactions and drug–disease relations. However, these binary relations cannot fully represent the original biomedical data. Therefore, there is a need for methods that can extract fine-grained and complex relations known as biomedical events. Results: In this article we propose a novel method to extract biomedical events from text. Our method consists of two phases. In the first phase, training data are mapped into structured representations. Based on that, templates are used to extract rules automatically. In the second phase, extraction methods are developed to process the obtained rules. When evaluated against the Genia event extraction abstract and full-text test datasets (Task 1), we obtain results with F-scores of 52.34 and 53.34, respectively, which are comparable to the state-of-the-art systems. Furthermore, our system achieves superior performance in terms of computational efficiency. Published version 2013-06-10T04:14:45Z 2019-12-06T19:25:22Z 2013-06-10T04:14:45Z 2019-12-06T19:25:22Z 2012 2012 Journal Article Bui, Q. C. & Sloot, P. M. A. (2012). A robust approach to extract biomedical events from literature. Bioinformatics, 28(20), 2654-2661. https://hdl.handle.net/10356/96085 http://hdl.handle.net/10220/10109 10.1093/bioinformatics/bts487 en Bioinformatics © 2012 The Author(s). Published by Oxford University Press. This paper was published in Bioinformatics and is made available as an electronic reprint (preprint) with permission of The Author(s). The paper can be found at the following official DOI: [http://dx.doi.org/10.1093/bioinformatics/bts487].  One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description Motivation: The abundance of biomedical literature has attracted significant interest in novel methods to automatically extract biomedical relations from the literature. Until recently, most research was focused on extracting binary relations such as protein–protein interactions and drug–disease relations. However, these binary relations cannot fully represent the original biomedical data. Therefore, there is a need for methods that can extract fine-grained and complex relations known as biomedical events. Results: In this article we propose a novel method to extract biomedical events from text. Our method consists of two phases. In the first phase, training data are mapped into structured representations. Based on that, templates are used to extract rules automatically. In the second phase, extraction methods are developed to process the obtained rules. When evaluated against the Genia event extraction abstract and full-text test datasets (Task 1), we obtain results with F-scores of 52.34 and 53.34, respectively, which are comparable to the state-of-the-art systems. Furthermore, our system achieves superior performance in terms of computational efficiency.
author2 School of Computer Engineering
author_facet School of Computer Engineering
Bui, Quoc-Chinh
Sloot, Peter M. A.
format Article
author Bui, Quoc-Chinh
Sloot, Peter M. A.
spellingShingle Bui, Quoc-Chinh
Sloot, Peter M. A.
A robust approach to extract biomedical events from literature
author_sort Bui, Quoc-Chinh
title A robust approach to extract biomedical events from literature
title_short A robust approach to extract biomedical events from literature
title_full A robust approach to extract biomedical events from literature
title_fullStr A robust approach to extract biomedical events from literature
title_full_unstemmed A robust approach to extract biomedical events from literature
title_sort robust approach to extract biomedical events from literature
publishDate 2013
url https://hdl.handle.net/10356/96085
http://hdl.handle.net/10220/10109
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