Investigating the influence of ionic concentrations and subunit interactions on the self-assembly of E2 protein

• Main Authors: Peng, Tao, Tan, Sze Wah, Dharmawan, Ratna Ekawati, Lim, Sierin
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Conference or Workshop Item
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/96087; http://hdl.handle.net/10220/10105
• Institution: Nanyang Technological University

Understanding of self-assembly mechanism of viruslike protein cage is important in controlling release of molecular cargo for applications in drug delivery. E2 core protein is composed of 60 subunits which self-assemble into a hollow 25-nm porous protein cage. Due to its virus like dodecahedral stru...