Positive-unlabeled learning for disease gene identification

• Main Authors: Yang, Peng, Li, Xiaoli, Mei, Jian-Ping, Kwoh, Chee Keong, Ng, See-Kiong
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: https://hdl.handle.net/10356/96132; http://hdl.handle.net/10220/10776
• Institution: Nanyang Technological University

Background: Identifying disease genes from human genome is an important but challenging task in biomedical research. Machine learning methods can be applied to discover new disease genes based on the known ones. Existing machine learning methods typically use the known disease genes as the positive...