Site specific immobilization of a potent antimicrobial peptide onto silicone catheters: evaluation against urinary tract infection pathogens

• Main Authors: Mishra, Biswajit, Basu, Anindya, Chua, Ray Rong Yuan, Saravanan, Rathi, Tambyah, Paul Anantharajah, Ho, Bow, Chang, Matthew Wook, Leong, Susanna Su Jan
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Bacteria
• Online Access: https://hdl.handle.net/10356/96196; http://hdl.handle.net/10220/38476
• Institution: Nanyang Technological University

Bacterial colonization of urinary catheters is a common problem leading to Catheter Associated Urinary Tract Infections (CAUTIs) in patients, which result in high treatment costs and associated complications. Due to the advantages of antimicrobial peptides (AMPs) compared to most other antimicrobial...