Surface modification of polycaprolactone substrates using collagen-conjugated poly(methacrylic acid) brushes for the regulation of cell proliferation and endothelialisation

• Main Authors: Yuan, Shaojun, Xiong, Gordon M., Wang, Xiaoyan, Zhang, Sam, Choong, Cleo Swee Neo
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Materials
• Online Access: https://hdl.handle.net/10356/96283; http://hdl.handle.net/10220/11326
• Institution: Nanyang Technological University

The incorporation and presentation of cell recognition ligands on the surfaces of biodegradable blood-vessel implants to promote endothelialisation is considered to be a promising approach to prevent platelet aggregation and hence thrombogenesis. In this study, cell-adhesive collagen was covalently...