Small molecule targeting malaria merozoite surface protein-1 (MSP-1) prevent host invasion of divergent plasmodial species

• Main Authors: Chandramohanadas, Rajesh, Russell, B., Basappa, Liew, K., Yau, Y. H., Chong, A., Min, L., Gunalan, K., Raman, R., Renia, L., Nosten, F., Shochat, S. G., Dao, M., Sasisekharan, R., Suresh, S., Preiser, P.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2014
• 主題: DRNTU::Science::Biological sciences
• 在線閱讀: https://hdl.handle.net/10356/96464; http://hdl.handle.net/10220/19458

Malaria causes nearly 1 million deaths annually. Recent emergence of multi-drug resistance highlights the need to develop novel therapeutic interventions against human malaria. Given the involvement of sugar binding plasmodial proteins in host invasion, we set out to identify such proteins as target...