Improving ethanol tolerance of Escherichia coli by rewiring Its global regulator cAMP receptor protein (CRP)

• المؤلفون الرئيسيون: Chong, Huiqing, Huang, Lei, Yeow, Jianwei, Wang, Ivy, Zhang, Hongfang, Song, Hao, Jiang, Rongrong
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Biological sciences::Genetics
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/96553; http://hdl.handle.net/10220/9887

A major challenge in bioethanol fermentation is the low tolerance of the microbial host towards the end product bioethanol. Here we report to improve the ethanol tolerance of E. coli from the transcriptional level by engineering its global transcription factor cAMP receptor protein (CRP), which is...