Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells

• Main Authors: Messersmith, Phillip B., Stanton, Lawrence W., Low, Wei Ching, Rujitanaroj, Pim-On, Lee, Dong-Kuen, Goh, Eyleen, Chew, Sing Yian
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/96593; http://hdl.handle.net/10220/9965
• Institution: Nanyang Technological University

At present, the recovery prospect for patients with chronic neurodegenerative diseases or acute trauma in the central nervous system is sub-optimal. The controlled differentiation of neural stem/progenitor cells (NPCs) to functional neurons is a possible treatment strategy. In contrast to the classi...