The polyelectrolyte properties of chromatin

• Main Authors: Nordenskiöld, Lars, Korolev, Nikolay, Allahverdi, Abdollah, Lyubartsev, Alexander P.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/96624; http://hdl.handle.net/10220/10352
• Institution: Nanyang Technological University

Double helical DNA is a negatively charged polyelectrolyte and exists in the nucleus of living cells as chromatin, a highly compacted but dynamic complex with histone proteins. The first level of DNA compaction is the linear array of the nucleosome core particles (NCP), which is a well-defined struc...