Functional divergence of FimX in PilZ binding and Type IV pilus regulation

• Main Authors: Qi, Yaning, Xu, Linghui, Dong, Xueming, Yau, Yin Hoe, Ho, Chun Loong, Koh, Siew Lee, Shochat, Susana Geifman, Chou, Shan-Ho, Tang, Kai, Liang, Zhao-Xun
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/96813; http://hdl.handle.net/10220/11648
• Institution: Nanyang Technological University

Type IV pili (T4P) are polar surface structures that play important roles in bacterial motility, biofilm formation, and pathogenicity. The protein FimX and its orthologs are known to mediate T4P formation in the human pathogen Pseudomonas aeruginosa and some other bacterial species. It was reported...