Heuristic modeling of macromolecule release from PLGA microspheres

• Main Authors: Paclawski, Adam, Lau, Raymond, Jachowicz, Renata, Mendyk, Aleksander, Szlk, Jakub
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine::Biomedical engineering
• Online Access: https://hdl.handle.net/10356/96865; http://hdl.handle.net/10220/24037
• Institution: Nanyang Technological University

Dissolution of protein macromolecules from poly(lactic-co-glycolic acid) (PLGA) particles is a complex process and still not fully understood. As such, there are difficulties in obtaining a predictive model that could be of fundamental significance in design, development, and optimization for medica...