N-Heterocyclic Carbene (NHC)-catalyzed highly diastereo- and enantioselective oxo-diels–alder reactions for synthesis of fused pyrano[2,3-b]indoles

N-Heterocyclic Carbene (NHC)-catalyzed highly diastereo- and enantioselective oxo-diels–alder reactions for synthesis of fused pyrano[2,3-b]indoles

A chiral N-heterocyclic carbene (NHC)-catalyzed Diels–Alder reaction of 2-oxoindolin-3-ylidenes and α-chloroaldehydes was developed for the synthesis of fused pyrano[2,3-b]indoles in good to excellent yields (up to 99%) with high cis-diastereoselectivities (>99:1 dr) and enantioselectivities (up...

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Bibliographic Details
Main Authors: Yang, Limin, Wang, Fei, Chua, Pei Juan, Lv, Yunbo, Zhong, Liang-Jun, Zhong, Guofu
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/97434
http://hdl.handle.net/10220/10604
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/97434
http://hdl.handle.net/10220/10604

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