Pentanidium–catalyzed enantioselective α-hydroxylation of oxindoles using molecular oxygen

• Main Authors: Yang, Yuanyong, Moinodeen, Farhana, Chin, Willy, Ma, Ting, Jiang, Zhiyong, Tan, Choon-Hong
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/97470; http://hdl.handle.net/10220/10584
• Institution: Nanyang Technological University

Pentanidium-catalyzed α-hydroxylation of 3-substituted-2-oxindoles using molecular oxygen has been developed with good yields and enantioselectivities. This reaction does not require an additional reductant such as triethyl phosphite, which was typically added to reduce the peroxide intermediate. Th...