Preparation of thin oligopeptide films using self-organized dendrimer monolayer as an anchoring scaffold

• Main Authors: Zhuang, Wensheng, Zhang, Hua, Liu, Daojun
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Materials::Microelectronics and semiconductor materials::Thin films
• Online Access: https://hdl.handle.net/10356/97514; http://hdl.handle.net/10220/10517
• Institution: Nanyang Technological University

Functionalization of a self-organized poly(amidoamine) (PAMAM) dendrimer monolayer with oligopeptides on a silicon/quartz substrate is investigated in this paper. A monolayer of PAMAM dendrimers is formed on a silicon/quartz surface via electrostatic adsorption. The functionalization of the PAMAM monolayer with oligo-tryptophan (Trp) is performed by in situ ring-opening polymerization of Trp–N-carboxyanhydrides (NCAs). The substrates have been examined by atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS) and UV–Vis spectroscopy, which confirm that the self-organized PAMAM dendrimer monolayer can be used as an anchoring scaffold for the construction of thin oligopeptide film.