NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death

• Main Authors: Feng, XiaoLing, Zhao, Yan, Lim, Chuan Bian, Fu, Pan You, Ky, Nung, Zhu, Hong Shuang, Li, Jinming, Srinivasan, Kandhadayar Gopalan, Hamza, Mohamed Sabry
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/97553; http://hdl.handle.net/10220/10581
• Institution: Nanyang Technological University

Background. Numerous studies have demonstrated that autophagy plays a vital role in maintaining cellular homeostasis. Interestingly, several anticancer agents were found to exert their anticancer effects by triggering autophagy. Emerging data suggest that autophagy represents a novel mechanism that...