Engineering of erythrocyte-based drug carriers : control of protein release and bioactivity

• Main Authors: Luo, Rongcong, Shaillender, Mutukumaraswamy, Venkatraman, Subbu S., Neu, Björn
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/97719; http://hdl.handle.net/10220/18105
• Institution: Nanyang Technological University

This work reports the fabrication of layer-by-layer (LbL) polyelectrolyte coated erythrocyte carriers that provide a simple means for controlling the burst and subsequent release of lysozyme. Erythrocytes were loaded with RITC-lysozyme as model compound via the hypotonic dialysis method. An encapsul...