Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA

• Main Authors: Nordin, N., Engman, H., Lundback, A.-K., Phua, T., Jong, Agnes Jin Oi, Cornvik, Tobias Carl, Guskov, Albert, Reynaud, Aline, Eshaghi, Said
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/97900; http://hdl.handle.net/10220/12345
• Institution: Nanyang Technological University

Despite the importance of Mg2+ for numerous cellular activities, the mechanisms underlying its import and homeostasis are poorly understood. The CorA family is ubiquitous and is primarily responsible for Mg2+ transport. However, the key questions—such as, the ion selectivity, the transport pathway,...