Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors

We have analyzed and compared the spectral differential phase sensing performance for conventional and long-range (LR) surface plasmon resonance (SPR) across a wide sample refractive index range (i.e. dynamic range) of 1.3330- 1.3505 using Fresnel's Equations and Transfer Matrix method. We demo...

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Main Authors: Shum, Perry Ping, Wang, Cheng, Ho, Ho-Pui
Other Authors: School of Electrical and Electronic Engineering
Format: Conference or Workshop Item
Language:English
Published: 2013
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Online Access:https://hdl.handle.net/10356/97904
http://hdl.handle.net/10220/12343
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-979042020-03-07T13:24:48Z Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors Shum, Perry Ping Wang, Cheng Ho, Ho-Pui School of Electrical and Electronic Engineering Plasmonics in Biology and Medicine (9th : 2012 : San Francisco, USA) DRNTU::Engineering::Electrical and electronic engineering We have analyzed and compared the spectral differential phase sensing performance for conventional and long-range (LR) surface plasmon resonance (SPR) across a wide sample refractive index range (i.e. dynamic range) of 1.3330- 1.3505 using Fresnel's Equations and Transfer Matrix method. We demonstrate that wide-range detection limit as high as 7.9×10-9 RIU (Refractive Index Unit) for conventional SPR can be achieved with a set of optimized sensing parameters and a phase measurement resolution of 2×10-4 rad, whereas best detection limit for LRSPR is lower. We have also investigated for the effect of sensing parameters including angle of incidence, metal film material and thickness. LRSPR is found to be quite tolerant to the choice of material and thickness of metal film. This work presents a comprehensive comparison between conventional and LR SPR for spectral-phase configuration. Published Version 2013-07-26T02:26:29Z 2019-12-06T19:48:07Z 2013-07-26T02:26:29Z 2019-12-06T19:48:07Z 2012 2012 Conference Paper Wang, C., Ho, H. P., & Shum, P. (2012). Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors. Proceedings of SPIE - Plasmonics in Biology and Medicine IX, 823414. https://hdl.handle.net/10356/97904 http://hdl.handle.net/10220/12343 10.1117/12.906756 en © 2012 SPIE. This paper was published in Proceedings of SPIE - Plasmonics in Biology and Medicine IX and is made available as an electronic reprint (preprint) with permission of SPIE. The paper can be found at the following official DOI: [http://dx.doi.org/10.1117/12.906756]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Electrical and electronic engineering
spellingShingle DRNTU::Engineering::Electrical and electronic engineering
Shum, Perry Ping
Wang, Cheng
Ho, Ho-Pui
Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
description We have analyzed and compared the spectral differential phase sensing performance for conventional and long-range (LR) surface plasmon resonance (SPR) across a wide sample refractive index range (i.e. dynamic range) of 1.3330- 1.3505 using Fresnel's Equations and Transfer Matrix method. We demonstrate that wide-range detection limit as high as 7.9×10-9 RIU (Refractive Index Unit) for conventional SPR can be achieved with a set of optimized sensing parameters and a phase measurement resolution of 2×10-4 rad, whereas best detection limit for LRSPR is lower. We have also investigated for the effect of sensing parameters including angle of incidence, metal film material and thickness. LRSPR is found to be quite tolerant to the choice of material and thickness of metal film. This work presents a comprehensive comparison between conventional and LR SPR for spectral-phase configuration.
author2 School of Electrical and Electronic Engineering
author_facet School of Electrical and Electronic Engineering
Shum, Perry Ping
Wang, Cheng
Ho, Ho-Pui
format Conference or Workshop Item
author Shum, Perry Ping
Wang, Cheng
Ho, Ho-Pui
author_sort Shum, Perry Ping
title Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
title_short Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
title_full Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
title_fullStr Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
title_full_unstemmed Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
title_sort analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
publishDate 2013
url https://hdl.handle.net/10356/97904
http://hdl.handle.net/10220/12343
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