Molecular dynamics simulation study on the molecular structures of the amylin fibril models

• Main Authors: Xu, Weixin, Su, Haibin, Mu, Yuguang, Zhang, John Z. H.
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2013
• 主題: DRNTU::Science::Chemistry::Physical chemistry
• 在線閱讀: https://hdl.handle.net/10356/97982; http://hdl.handle.net/10220/17172

The structural characterization of amyloid fibers is one of the most investigated areas in structural biology. Recently, protofibril models for amylin, i.e., the 37-residue human islet amyloid polypeptide or hIAPP were suggested by two groups based on NMR ( Biochemistry 2007, 46, 13505−13522) and X-...