Calcineurin/NFAT signalling inhibits myeloid haematopoiesis

• Main Authors: Fric, Jan, Hofmann, Benjamin, Chen, Jinmiao, Tay, Hock Soon, Siti Aminah Mohammad Isa, Mortellaro, Alessandra, Ruedl, Christiane, Ricciardi-Castagnoli, Paola, Lim, Clarice X. F., Koh, Esther G. L.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/98079; http://hdl.handle.net/10220/13277
• Institution: Nanyang Technological University

Nuclear factor of activated T cells (NFAT) comprises a family of transcription factors that regulate T cell development, activation and differentiation. NFAT signalling can also mediate granulocyte and dendritic cell (DC) activation, but it is unknown whether NFAT influences their development fro...