Fast reconstruction of Raman spectra from narrow-band measurements based on Wiener estimation
Raman spectroscopy has demonstrated great potential in the study of biological molecules in a variety of biomedical applications. But slow data acquisition due to weak Raman signals from these molecules has prevented its wide use especially in an imaging setup. We propose a novel method to reconstru...
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/98142 http://hdl.handle.net/10220/12300 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Raman spectroscopy has demonstrated great potential in the study of biological molecules in a variety of biomedical applications. But slow data acquisition due to weak Raman signals from these molecules has prevented its wide use especially in an imaging setup. We propose a novel method to reconstruct the entire Raman spectrum from a few narrow-band measurements based on Wiener estimation. This method has been tested on Raman spectra from individual cells and shown fast speed and excellent accuracy. This method represents a new direction to speed up Raman data acquisition in an imaging setup to investigate fast changing phenomena. |
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