Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing

• Main Authors: Liu, Yang, Dong, Yongqiang, Guo, Chun Xian, Cui, Zhiming, Zheng, Lianxi, Li, Chang Ming
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/98177; http://hdl.handle.net/10220/13259
• Institution: Nanyang Technological University

A novel nonenzymatic glucose sensor was developed based on well-dispersed gold nanoparticles, which were in situ grown under direction of protein on a reduced graphene oxide modified electrode. This electrode exhibited high electrocatalytic activity towards glucose oxidation without use of any enzyme or mediator. In application for the amperometric detection of glucose, a wide linear range of 0.02–16.6 mM, low detection limit of 5 mM and good selectivity were obtained. The attractive analytical performances of the proposed glucose sensor, coupled with the facile preparation method, provide a promising electrochemical platform for the development of effective nonenzymatic sensors.