Iron(III)-catalyzed conia–ene cyclization of 2-alkynic 1,3-dicarbonyl compounds

• Main Authors: Chan, Li Yan, Kim, Sunggak, Park, Youngchul, Lee, Phil Ho
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Chemistry::Organic chemistry
• Online Access: https://hdl.handle.net/10356/98328; http://hdl.handle.net/10220/17135
• Institution: Nanyang Technological University

A cheap, simple, and effective FeCl3-catalyzed Conia–ene cyclization of 2-alkynic 1,3-dicarbonyl compounds was stereospecific to afford alkylidenecyclopentanes in (E)-isomers via the 5-exo-dig pathway. The 5-endo-dig and 6-exo-dig cyclizations were also possible, depending on the structure of the su...