Highly enantio- and diastereoselective reactions of γ-substituted butenolides through direct vinylogous conjugate additions

The strength of the weak: An L-tert-leucine-derived amine–thiourea catalyst (see scheme, green box) promotes the asymmetric vinylogous conjugate addition reaction between γ-aryl- and alkyl-substituted butenolides with the butenamides and enoates shown. Computational studies show the preference for t...

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Bibliographic Details
Main Authors: Zhang, Wen, Tan, Davin, Lee, Richmond, Tong, Guanghu, Chen, Wenchao, Qi, Baojian, Huang, Kuo-Wei, Tan, Choon-Hong, Jiang, Zhiyong
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/98442
http://hdl.handle.net/10220/12455
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Institution: Nanyang Technological University
Language: English
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