Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors

Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors

A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO2 wafer using the Langmuir–Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as t...

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Bibliographic Details
Main Authors: Yin, Zongyou, He, Qiyuan, Huang, Xiao, Zhang, Juan, Wu, Shixin, Chen, Peng, Lu, Gang, Zhang, Qichun, Yan, Qingyu, Zhang, Hua
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/98450
http://hdl.handle.net/10220/10690
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Institution: Nanyang Technological University
Language: English
Description
Summary:A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO2 wafer using the Langmuir–Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.

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