Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications

Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications

Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their uniqu...

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Main Authors: Tng, Danny Jian Hang, Hu, Rui, Song, Peiyi, Roy, Indrajit, Yong, Ken-Tye
Other Authors: School of Electrical and Electronic Engineering
Format: Article
Language:English
Published: 2013
Subjects:
DRNTU::Engineering::Electrical and electronic engineering
Online Access:https://hdl.handle.net/10356/98500
http://hdl.handle.net/10220/10917
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-985002020-03-07T14:00:30Z Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications Tng, Danny Jian Hang Hu, Rui Song, Peiyi Roy, Indrajit Yong, Ken-Tye School of Electrical and Electronic Engineering DRNTU::Engineering::Electrical and electronic engineering Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their unique properties, microelectromechanical systems (MEMS) technology has been recently engineered as implantable drug delivery systems for disease therapy. This review examines the challenges faced in implementing implantable MEMS drug delivery systems in vivo and the solutions available to overcome these challenges. Published version 2013-07-04T01:56:12Z 2019-12-06T19:56:12Z 2013-07-04T01:56:12Z 2019-12-06T19:56:12Z 2012 2012 Journal Article Tng, D. J. H., Hu, R., Song, P., Roy, I., & Yong, K.-T. (2012). Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications. Micromachines, 3(4), 615-631. 2072-666X https://hdl.handle.net/10356/98500 http://hdl.handle.net/10220/10917 10.3390/mi3040615 en Micromachines © 2012 The Author(s) (published by MDPI). This paper was published in Micromachines and is made available as an electronic reprint (preprint) with permission of The Author(s) (published by MDPI). The paper can be found at the following official DOI: [http://dx.doi.org/10.3390/mi3040615]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Electrical and electronic engineering
spellingShingle DRNTU::Engineering::Electrical and electronic engineering
Tng, Danny Jian Hang
Hu, Rui
Song, Peiyi
Roy, Indrajit
Yong, Ken-Tye
Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications
description Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their unique properties, microelectromechanical systems (MEMS) technology has been recently engineered as implantable drug delivery systems for disease therapy. This review examines the challenges faced in implementing implantable MEMS drug delivery systems in vivo and the solutions available to overcome these challenges.
author2 School of Electrical and Electronic Engineering
author_facet School of Electrical and Electronic Engineering
Tng, Danny Jian Hang
Hu, Rui
Song, Peiyi
Roy, Indrajit
Yong, Ken-Tye
format Article
author Tng, Danny Jian Hang
Hu, Rui
Song, Peiyi
Roy, Indrajit
Yong, Ken-Tye
author_sort Tng, Danny Jian Hang
title Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications
title_short Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications
title_full Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications
title_fullStr Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications
title_full_unstemmed Approaches and challenges of engineering implantable microelectromechanical systems (MEMS) drug delivery systems for in vitro and in vivo applications
title_sort approaches and challenges of engineering implantable microelectromechanical systems (mems) drug delivery systems for in vitro and in vivo applications
publishDate 2013
url https://hdl.handle.net/10356/98500
http://hdl.handle.net/10220/10917
_version_ 1681041650008195072

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