Following G-quadruplex formation by its intrinsic fluorescence
We characterized and compared the fluorescence properties of various well-defined G-quadruplex structures. The increase of intrinsic fluorescence of G-rich DNA sequences when they form G-quadruplexes can be used to monitor the folding and unfolding of G-quadruplexes as a function of cations and temp...
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sg-ntu-dr.10356-986182023-02-28T19:32:07Z Following G-quadruplex formation by its intrinsic fluorescence Dao, Nguyen Thuan Reinhard, Haselsberger Maria-Elisabeth, Michel-Beyerle Phan, Anh Tuân School of Physical and Mathematical Sciences DRNTU::Science::Chemistry We characterized and compared the fluorescence properties of various well-defined G-quadruplex structures. The increase of intrinsic fluorescence of G-rich DNA sequences when they form G-quadruplexes can be used to monitor the folding and unfolding of G-quadruplexes as a function of cations and temperature. The temperature-dependent fluorescence spectra of different G-quadruplexes also exhibit characteristic patterns. Thus, the stability and possibly also the structure of G-quadruplexes can be characterized and distinguished by their intrinsic fluorescence spectra. Accepted version 2013-07-29T07:09:09Z 2019-12-06T19:57:43Z 2013-07-29T07:09:09Z 2019-12-06T19:57:43Z 2011 2011 Journal Article Dao, N.T., Reinhard, H., Maria-Elisabeth, M.-B., & Phan, A.T. (2012). Following G-quadruplex formation by its intrinsic fluorescence. FEBS Letter, 585(24), 3969–3977. 0014-5793 https://hdl.handle.net/10356/98618 http://hdl.handle.net/10220/12476 10.1016/j.febslet.2011.11.004 en FEBS letter © 2011 Federation of European Biochemical Societies. This is the author created version of a work that has been peer reviewed and accepted for publication in FEBS letter, published by Elsevier B.V. on behalf of Federation of European Biochemical Societies. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI:http://dx.doi.org/10.1016/j.febslet.2011.11.004]. application/pdf |
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DRNTU::Science::Chemistry Dao, Nguyen Thuan Reinhard, Haselsberger Maria-Elisabeth, Michel-Beyerle Phan, Anh Tuân Following G-quadruplex formation by its intrinsic fluorescence |
| description |
We characterized and compared the fluorescence properties of various well-defined G-quadruplex structures. The increase of intrinsic fluorescence of G-rich DNA sequences when they form G-quadruplexes can be used to monitor the folding and unfolding of G-quadruplexes as a function of cations and temperature. The temperature-dependent fluorescence spectra of different G-quadruplexes also exhibit characteristic patterns. Thus, the stability and possibly also the structure of G-quadruplexes can be characterized and distinguished by their intrinsic fluorescence spectra. |
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School of Physical and Mathematical Sciences |
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School of Physical and Mathematical Sciences Dao, Nguyen Thuan Reinhard, Haselsberger Maria-Elisabeth, Michel-Beyerle Phan, Anh Tuân |
| format |
Article |
| author |
Dao, Nguyen Thuan Reinhard, Haselsberger Maria-Elisabeth, Michel-Beyerle Phan, Anh Tuân |
| author_sort |
Dao, Nguyen Thuan |
| title |
Following G-quadruplex formation by its intrinsic fluorescence |
| title_short |
Following G-quadruplex formation by its intrinsic fluorescence |
| title_full |
Following G-quadruplex formation by its intrinsic fluorescence |
| title_fullStr |
Following G-quadruplex formation by its intrinsic fluorescence |
| title_full_unstemmed |
Following G-quadruplex formation by its intrinsic fluorescence |
| title_sort |
following g-quadruplex formation by its intrinsic fluorescence |
| publishDate |
2013 |
| url |
https://hdl.handle.net/10356/98618 http://hdl.handle.net/10220/12476 |
| _version_ |
1759854488276959232 |