The role of the reticulocyte-binding-like protein homologues of Plasmodium in erythrocyte sensing and invasion

• Main Authors: Gunalan, Karthigayan, Gao, Xiaohong, Yap, Sally Shu Lin, Huang, Ximei, Preiser, Peter Rainer
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Microbiology
• Online Access: https://hdl.handle.net/10356/98650; http://hdl.handle.net/10220/17542
• Institution: Nanyang Technological University

Malaria remains a serious public health problem with significant morbidity and mortality accounting for nearly 20% of all childhood deaths in Africa. The cyclical invasion, cytoadherence and destruction of the host's erythrocyte by the parasite are responsible for the observed disease pathology...