Sonolysis of Escherichia coli and Pichia pastoris in microfluidics

• Main Authors: Tandiono, Tandiono, Siak-Wei Ow, Dave, Driessen, Leonie, Sze-Hui Chin, Cara, Klaseboer, Evert, Boon-Hwa Choo, Andre, Ohl, Siew-Wan, Ohl, Claus-Dieter
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Chemistry
• Online Access: https://hdl.handle.net/10356/98659; http://hdl.handle.net/10220/17977
• Institution: Nanyang Technological University

We report on an efficient ultrasound based technique for lysing Escherichia coli and Pichia pastoris with oscillating cavitation bubbles in an integrated microfluidic system. The system consists of a meandering microfluidic channel and four piezoelectric transducers mounted on a glass substrate, wit...