Nanotube-supported bioproduction of 4-hydroxy-2-butanone via in situ cofactor regeneration

• Main Authors: Jiang, Rongrong, Wang, Liang, Zhang, Hongfang, Ching, Chi Bun, Chen, Yuan
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology
• Online Access: https://hdl.handle.net/10356/98811; http://hdl.handle.net/10220/12523
• Institution: Nanyang Technological University

Nicotinamide cofactor-dependent oxidoreductases have been widely employed during the bioproduction of varieties of useful compounds. Efficient cofactor regeneration is often required for these biotransformation reactions. Herein, we report the synthesis of an important pharmaceutical intermediate 4-...