Randomized, controlled trial of a sustained delivery formulation of 5-Fluorouracil for the treatment of failing blebs

• Main Authors: Narayanaswamy, Arun Kumar, Lee, Kelvin, Zhen, Ma, Chua, Jocelyn, Chai, Shu Ming, Boey, Pui Yi, Zheng, Ce, Aung, Tin, Venkatraman, Subramanian, Wong, Tina Tzee Ling
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/98884; http://hdl.handle.net/10220/17114
• Institution: Nanyang Technological University

Purpose: To determine the efficacy of a subconjunctival injection of hyaluronic acid (HA) with 5-fluorouracil (5FU) formulation as an adjunct in reviving bleb function by needling. Design: Prospective, randomized, controlled trial. Participants: Fifty patients with previous trabeculectomy and sc...