Temporal control over cellular targeting through hybridization of folate-targeted dendrimers and PEG-PLA nanoparticles

• Main Authors: Sunoqrot, Suhair, Bae, Jin Woo, Shyu, Kevin, Liu, Ying, Kim, Dong-Hwan, Hong, Seungpyo, Pearson, Ryan M.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/98957; http://hdl.handle.net/10220/12814
• Institution: Nanyang Technological University

Polymeric nanoparticles (NPs) and dendrimers are two major classes of nanomaterials that have demonstrated great potential for targeted drug delivery. However, their targeting efficacy has not yet met clinical needs, largely because of a lack of control over their targeting kinetics, which often res...