Computational study of bindings of HK20 Fab and D5 Fab to HIV-1 gp41
Antibodies HK20 and D5 have been shown to target HIV-1 gp41, thereby inhibiting membrane fusion that facilitates viral entry. The binding picture is static, based on the X-ray crystal structures of the Fab regions and gp41 mimetic five-helix bundle. In this study, we carried out molecular dynamics s...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/99036 http://hdl.handle.net/10220/12790 |
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| Institution: | Nanyang Technological University |
| Language: | English |