Teasing apart translational and transcriptional components of stochastic variations in eukaryotic gene expression

• Main Authors: Przytycka, Teresa M., Salari, Raheleh, Wojtowicz, Damian, Zheng, Jie, Levens, David, Pilpel, Yitzhak
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: https://hdl.handle.net/10356/99095; http://hdl.handle.net/10220/10925
• Institution: Nanyang Technological University

The intrinsic stochasticity of gene expression leads to cell-to-cell variations, noise, in protein abundance. Several processes, including transcription, translation, and degradation of mRNA and proteins, can contribute to these variations. Recent single cell analyses of gene expression in yeast hav...