The intrinsic helical propensities of the helical fragments in prion protein under neutral and low pH conditions : a replica exchange molecular dynamics study

The intrinsic helical propensities of the helical fragments in prion protein under neutral and low pH conditions : a replica exchange molecular dynamics study

Replica exchange molecular dynamics simulations in neutral and acidic aqueous solutions were employed to study the intrinsic helical propensities of three helices in both Syrian hamster (syPrP) and human (huPrP) prion proteins. The helical propensities of syPrP HA and huPrP HA are very high under bo...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang, John Z. H., Lu, Xiaoliang, Zeng, Juan, Gao, Ya, Zhang, Dawei, Mei, Ye
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99170
http://hdl.handle.net/10220/17372
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/99170
http://hdl.handle.net/10220/17372

Similar Items