Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice

• Main Authors: Li, Y., Kundu, P., Seow, S. W., de Matos, C. T., Aronsson, L., Chin, K. C., Karre, K., Pettersson, S., Greicius, G.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/99214; http://hdl.handle.net/10220/12791
• Institution: Nanyang Technological University

Chronic inflammation is increasingly recognized as a major contributor of human colorectal cancer (CRC). While gut microbiota can trigger inflammation in the intestinal tract, the precise signaling pathways through which host cells respond to inflammatory bacterial stimulation are unclear. Here, we...