Asymmetric hetero-diels–alder reaction of Danishefsky’s dienes with α-carbonyl esters catalyzed by an indium(III)–PyBox complex

Asymmetric hetero-diels–alder reaction of Danishefsky’s dienes with α-carbonyl esters catalyzed by an indium(III)–PyBox complex

An efficient catalytic enantioselective hetero-Diels–Alder reaction of Danishefsky’s dienes with α-carbonyl esters using a chiral In(III)–pybox complex has been demonstrated. This protocol offers several advantages, including mild reaction conditions, relatively low catalyst loading, and good to exc...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhao, Bei, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Chemistry and Biological Chemistry
Online Access:https://hdl.handle.net/10356/99263
http://hdl.handle.net/10220/17487
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Description
Summary:An efficient catalytic enantioselective hetero-Diels–Alder reaction of Danishefsky’s dienes with α-carbonyl esters using a chiral In(III)–pybox complex has been demonstrated. This protocol offers several advantages, including mild reaction conditions, relatively low catalyst loading, and good to excellent enantioselectivities. Furthermore, the absolute configurations of the new alkynyl-containing products were determined by CD spectra in combination with TD-DFT calculations.

Similar Items