Antimicrobial functionalization of silicone surfaces with engineered short peptides having broad spectrum antimicrobial and salt-resistant properties

• Main Authors: Li, Xiang, Li, Peng, Saravanan, Rathi, Basu, Anindya, Mishra, Biswajit, Lim, Suo Hon, Su, Xiaodi, Tambyah, Paul Anantharajah, Leong, Susanna Su Jan
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/99360; http://hdl.handle.net/10220/17670
• Institution: Nanyang Technological University

Catheter-associated urinary tract infections (CAUTIs) are often preceded by pathogen colonization on catheter surfaces and are a major health threat facing hospitals worldwide. Antimicrobial peptides (AMPs) are a class of new antibiotics that hold promise in curbing CAUTIs caused by antibiotic-resis...