Review of vascularised bone tissue-engineering strategies with a focus on co-culture systems

• Main Authors: Liu, Yuchun, Chan, Jerry Kok Yen, Teoh, Swee-Hin
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Medicine::Tissue engineering
• Online Access: https://hdl.handle.net/10356/99380; http://hdl.handle.net/10220/17140
• Institution: Nanyang Technological University

Poor angiogenesis within tissue-engineered grafts has been identified as a main challenge limiting the clinical introduction of bone tissue-engineering (BTE) approaches for the repair of large bone defects. Thick BTE grafts often exhibit poor cellular viability particularly at the core, leading to g...