Characterizing the neurite outgrowth inhibitory effect of Mani

• Main Authors: Mishra, Manisha, Lee, Sachiko, Yamashita, Toshihide, Heese, Klaus, Lin, Michelle K.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/99385; http://hdl.handle.net/10220/16250
• Institution: Nanyang Technological University

Mani (myelin-associated neurite-outgrowth inhibitor) protein is implicated in both axonal guidance and axonal regeneration after central nervous system (CNS) injury. Here, we applied a neurite outgrowth assay, coupled with a siRNA-driven investigation and immunocytochemistry, to unveil Mani’s axonal...