Palladium-catalyzed cross-coupling of unactivated alkenes with Acrylates: application to the synthesis of the C13-C21 fragment of Palmerolide A

• Main Authors: Wen, Zhen-Kang, Xu, Yun-He, Loh, Teck-Peng
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/99508; http://hdl.handle.net/10220/12903
• Institution: Nanyang Technological University

Diene to meet: A palladium-catalyzed cross-coupling reaction between alkyl-substituted olefins and acrylates gives the corresponding butadienes in moderate yield and stereoselectivity. This atom-economical reaction, which forms Cmath image–Cmath image bonds, tolerates a wide range of allylic and hom...