Synergism between Curdlan and GM-CSF confers a strong inflammatory signature to Dendritic cells

• Main Authors: Min, Lin, Siti Aminah Mohammad Isa, Fam, Wee Nih, Sze, Siu Kwan, Beretta, Ottavio, Mortellaro, Alessandra, Ruedl, Christiane
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/99524; http://hdl.handle.net/10220/12908
• Institution: Nanyang Technological University

A simultaneous engagement of different pathogen recognition receptors provides a tailor-made adaptive immunity for an efficient defense against distinct pathogens. For example, cross-talk of TLR and C-type lectin signaling effectively shapes distinct gene expression patterns by integrating the signa...