N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes : asymmetric synthesis of 5-carbon-synthon δ-nitroesters

• Main Authors: Maji, Biswajit, Ji, Li, Wang, Siming, Vedachalam, Seenuvasan, Ganguly, Rakesh, Liu, Xue-Wei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Chemistry
• Online Access: https://hdl.handle.net/10356/99527; http://hdl.handle.net/10220/12504
• Institution: Nanyang Technological University

Synthesizing synthons: The highly enantioselective title reaction is described. It employs catalytic amounts of N-heterocyclic carbene precursors and transforms a broad range of nitroalkenes, such as nitrodienes, nitroenynes, and nitrostyrenes, through reaction with a broad range of enals, into δ-ni...