Cobalt-catalyzed ortho-alkenylation of aromatic aldimines via chelation-assisted C–H bond activation

• Main Authors: Yamakawa, Takeshi, Yoshikai, Naohiko
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2013
• 主題: DRNTU::Science::Chemistry::Organic chemistry
• 在線閱讀: https://hdl.handle.net/10356/99588; http://hdl.handle.net/10220/17467

An ortho-alkenylation reaction of an aromatic aldimine with an internal alkyne is efficiently promoted by a cobalt catalyst generated from CoBr2, triarylphosphine, and iPrMgBr. The reaction takes place under mild room-temperature conditions to afford, upon acidic hydrolysis, a variety of ortho-alken...